[TABLE OF CONTENTS PROSPECTUS SUPPLEMENT Use these links to rapidly review the document Title of each class of Amount to be Proposed maximum Proposed maximum Amount of Ordinary shares, par value $0.01 per share 4,096,875 $367.68 $1,506,339,000.00 $151,688.34 (1) These ordinary shares are represented by American depositary shares, each of which represents 0.125 of an ordinary share. The ADSs issuable]
[TABLE OF CONTENTS PROSPECTUS SUPPLEMENT Use these links to rapidly review the document Title of each class of Amount to be Proposed maximum Proposed maximum Amount of Ordinary shares, par value $0.01 per share 4,096,875 $367.68 $1,506,339,000.00 $151,688.34 (1) These ordinary shares are represented by American depositary shares, each of which represents 0.125 of an ordinary share. The ADSs issuable]
[Ctrip.com International, Ltd. Announces Pricing of Offering of American Depositary Shares SHANGHAI, September 7, 2016 Ctrip.com International, Ltd. (Nasdaq: CTRP), a leading travel service provider of accommodation reservation, transportation ticketing, packaged tours and corporate travel management in China (Ctrip or the Company), today announced the pricing of 28,500,000 American depositary shares (ADSs), each representing 0.125 of an ordinary share] [Ctrip.com International, Ltd. Prices Offering of Convertible Senior Notes The Company also priced the concurrent offering of 28,500,000 ADSs (the ADS Offering) at US$45.96 per ADS. Ctrip has granted the underwriters in the ADS Offering a 30-day option to purchase up to an additional 4,275,000 ADSs in connection with the ADS Offering to cover over-allotments, if any. The closing of] [001-33853 CTRIP.COM INTERNATIONAL, LTD. 968 Jin Zhong Road Shanghai 200335, Peoples Republic of China Form 20-F x Form 40-F o o o CTRIP.COM INTERNATIONAL, LTD.]
[Ctrip.com International, Ltd. Announces Pricing of Offering of American Depositary Shares SHANGHAI, September 7, 2016 Ctrip.com International, Ltd. (Nasdaq: CTRP), a leading travel service provider of accommodation reservation, transportation ticketing, packaged tours and corporate travel management in China (Ctrip or the Company), today announced the pricing of 28,500,000 American depositary shares (ADSs), each representing 0.125 of an ordinary share] [Ctrip.com International, Ltd. Prices Offering of Convertible Senior Notes The Company also priced the concurrent offering of 28,500,000 ADSs (the ADS Offering) at US$45.96 per ADS. Ctrip has granted the underwriters in the ADS Offering a 30-day option to purchase up to an additional 4,275,000 ADSs in connection with the ADS Offering to cover over-allotments, if any. The closing of] [001-33853 CTRIP.COM INTERNATIONAL, LTD. 968 Jin Zhong Road Shanghai 200335, Peoples Republic of China Form 20-F x Form 40-F o o o CTRIP.COM INTERNATIONAL, LTD.]
[QuickLinks -- Click here to rapidly navigate through this document https://www.sec.gov/Archives/edgar/data/1269238/000104746916015261/a2229623z424b5.htm This issuer free writing prospectus updates the information contained in the Preliminary Prospectus Supplement to reflect the increases in the number of ADSs being offered and the aggregate principal amount of our convertible notes, impact on net proceeds and capitalization tables, as well as certain other changes. The free]
[QuickLinks -- Click here to rapidly navigate through this document https://www.sec.gov/Archives/edgar/data/1269238/000104746916015261/a2229623z424b5.htm This issuer free writing prospectus updates the information contained in the Preliminary Prospectus Supplement to reflect the increases in the number of ADSs being offered and the aggregate principal amount of our convertible notes, impact on net proceeds and capitalization tables, as well as certain other changes. The free]
[The information in this preliminary prospectus supplement is not complete and may be changed. Neither this preliminary prospectus supplement nor the accompanying prospectus is an offer to sell these securities, nor does it solicit offers to buy these securities in any jurisdiction where the offer or sale is not permitted. SUBJECT TO COMPLETION. DATED SEPTEMBER 6, 2016. Prospectus Supplement Ctrip.com]
[QuickLinks -- Click here to rapidly navigate through this document Consent of Independent Registered Public Accounting Firm We consent to the reference to our firm under the caption "Experts" in the Registration Statement (Form F-3 No. 333-208399) and related Prospectus of Ctrip.com International, Ltd. and to the incorporation by reference therein of our report dated April 14, 2016, with respect] [QuickLinks -- Click here to rapidly navigate through this document Six-month Six-month Six-month RMB RMB US$ Revenues: Accommodation reservation 2,056,220,713 3,389,849,328 510,066,256 Transportation ticketing 2,000,458,455 3,952,429,921 594,717,032 Packaged-tour 725,286,233 1,030,426,993 155,047,020 Corporate travel 213,459,763 262,728,423 39,532,407 Others 113,366,310 306,098,841 46,058,298 Total revenues 5,108,791,474 8,941,533,506 1,345,421,013] [QuickLinks -- Click here to rapidly navigate through this document QUNAR CAYMAN ISLANDS LIMITED Page 1 Consolidated balance sheets as of December 31, 2014 and 2015 Consolidated statements of comprehensive loss for the years ended December 31, 2013, 2014 and 2015 Consolidated statements of cash flows for the years ended December 31, 2013, 2014 and 2015 Consolidated statements of shareholders'] [QuickLinks -- Click here to rapidly navigate through this document UNAUDITED PRO FORMA CONDENSED COMBINED FINANCIAL INFORMATION Ctrip.com International, Ltd. ("Ctrip" or the "Company") owned ordinary shares of Qunar Cayman Islands Limited ("Qunar") representing approximately 45% of Qunar's aggregate voting interest, after completing the share exchange transaction with Baidu, Inc. as announced on October 26, 2015. After the Company's issue] [CTRIP.COM INTERNATIONAL, LTD. 968 Jin Zhong Road ý o Form 20-F EXPLANATORY NOTE CTRIP.COM INTERNATIONAL, LTD. Xiaofan Wang]
[QuickLinks -- Click here to rapidly navigate through this document Consent of Independent Registered Public Accounting Firm We consent to the reference to our firm under the caption "Experts" in the Registration Statement (Form F-3 No. 333-208399) and related Prospectus of Ctrip.com International, Ltd. and to the incorporation by reference therein of our report dated April 14, 2016, with respect] [QuickLinks -- Click here to rapidly navigate through this document Six-month Six-month Six-month RMB RMB US$ Revenues: Accommodation reservation 2,056,220,713 3,389,849,328 510,066,256 Transportation ticketing 2,000,458,455 3,952,429,921 594,717,032 Packaged-tour 725,286,233 1,030,426,993 155,047,020 Corporate travel 213,459,763 262,728,423 39,532,407 Others 113,366,310 306,098,841 46,058,298 Total revenues 5,108,791,474 8,941,533,506 1,345,421,013] [QuickLinks -- Click here to rapidly navigate through this document QUNAR CAYMAN ISLANDS LIMITED Page 1 Consolidated balance sheets as of December 31, 2014 and 2015 Consolidated statements of comprehensive loss for the years ended December 31, 2013, 2014 and 2015 Consolidated statements of cash flows for the years ended December 31, 2013, 2014 and 2015 Consolidated statements of shareholders'] [QuickLinks -- Click here to rapidly navigate through this document UNAUDITED PRO FORMA CONDENSED COMBINED FINANCIAL INFORMATION Ctrip.com International, Ltd. ("Ctrip" or the "Company") owned ordinary shares of Qunar Cayman Islands Limited ("Qunar") representing approximately 45% of Qunar's aggregate voting interest, after completing the share exchange transaction with Baidu, Inc. as announced on October 26, 2015. After the Company's issue] [CTRIP.COM INTERNATIONAL, LTD. 968 Jin Zhong Road ý o Form 20-F EXPLANATORY NOTE CTRIP.COM INTERNATIONAL, LTD. Xiaofan Wang]
[CTRIP.COM INTERNATIONAL, LTD. [ · representing [ · (par value US$0.01 per share) Underwriting Agreement [ · J.P. Morgan J. P. Morgan Securities LLC ( 383 Madison Avenue New York, New York 10179 Morgan Stanley Morgan Stanley & Co. International plc ( 25 Cabot Square Canary Wharf London E14 4QA United Kingdom As the several Underwriters listed in Schedule 1] [001-33853 CTRIP.COM INTERNATIONAL, LTD. 968 Jin Zhong Road Shanghai 200335, Peoples Republic of China Form 20-F x Form 40-F o o o EXPLANATORY NOTE 2 CTRIP.COM INTERNATIONAL, LTD.]
